IGF2BP3 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 14642-1-AP

Featured Product KD/KO validated

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Con: 22 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HepG2 cells, BxPC-3 cells, HeLa cells, HepG2 cells, mouse brain tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human pancreas cancer tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
insulin-like growth factor 2 mRNA binding protein 3

Calculated molecular weight:
64 kDa

Observed molecular weight:
64 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IGF2BP3

Synonyms
DKFZp686F1078, hKOC, IGF II mRNA binding protein 3, IGF2 mRNA binding protein 3, IGF2BP3, IMP 3, IMP3, KOC1, VICKZ family member 3, VICKZ3
Background

IGF2BP3, also named as IMP3, KOC1 and VICKZ3, belongs to the RRM IMP/VICKZ family. It is one of the RNA binding proteins involved in mRNA localization and translational control. IGF2BP3 is expressed during embryogenesis, as well as in some malignant tumors. It can be used as an independent prognostic factor for osteosarcoma. Both isoforms (64kd and 22kd) of IGFBP3 can be recognized by this antibody. And IGFBP3 is nuclear and cytoplasm stains.


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