LAMP2 Antibody

LAMP2 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

IF, ELISA

Conjugate

Unconjugated

Cat no : 10397-1-AP

Synonyms

CD107b, LAMP 2, LAMP2, LAMPB, LGP110



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

10397-1-AP targets LAMP2 in IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LAMP2 fusion protein Ag0595
Full Name lysosomal-associated membrane protein 2
Calculated molecular weight 45 kDa
Observed molecular weight
GenBank accession number BC002965
Gene symbol LAMP2
Gene ID (NCBI) 3920
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.

Publications

SpeciesApplicationTitle
humanWB

Biochem Biophys Res Commun

Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.

Authors - Zhiqiang Li
mouseWB

Cell Mol Neurobiol

Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Authors - Sher Hayat Khan
humanWB

Food Chem Toxicol

Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.

Authors - Xiao-Feng Yao
humanWB

Chem Res Toxicol

Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.

Authors - Qiong Shi
humanWB

J Immunother

The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1.

Authors - Alatrash Gheath G
rat, mouseWB

Cell Biosci

Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.

Authors - Jiaqi Liu