Lin28B-specific Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 16178-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Transfected HEK-293 cells

Positive IHC detected in:
human testis tissue, human brain tissue, human kidney tissue, human liver cancer tissue, human lung tissue, human placenta tissue, human spleen tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
lin-28 homolog B (C. elegans)

Calculated molecular weight:
28 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LIN28B

Synonyms
CSDD2, FLJ16517, lin 28 homolog B (C. elegans), Lin 28B, Lin28, LIN28B, Protein lin 28 homolog B
Background

LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B.


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