NKRF Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14693-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 20 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, A431 cells, A549 cells, HepG2 cells, PC-3 cells

Positive IP detected in:
A549 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
NFKB repressing factor

Calculated molecular weight:
78 kDa

Observed molecular weight:
100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NKRF

Synonyms
ITBA4, NF kappa B repressing factor, NKRF, NRF, Protein ITBA4, Transcription factor NRF
Background

NKRF, also named as Protein ITBA4 or Transcription factor NRF, is a 690 amino acid protein, which contains one G-patch domain and one R3H domain. NKRF is Widely and constitutively expressed, with lower level in colon, peripheral blood lymphocytes, lung and kidney. NKRF interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. NKRF is involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity.


Back
to top