P2RX4 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13534-1-AP

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Freight/Packing

Con: 30 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A549 cells, human colon tissue, mouse brain tissue, SH-SY5Y cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human kidney tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue

Positive IF detected in:
HeLa cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
purinergic receptor P2X, ligand-gated ion channel, 4

Calculated molecular weight:
388aa,43 kDa

Observed molecular weight:
55-60kd,70-80kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
P2RX4

Synonyms
ATP receptor, P2RX4, P2X purinoceptor 4, P2X4, P2X4R, Purinergic receptor
Background

Nucleotides, the structural subunits of the nucleic acids, are also important extracellular signaling molecules. P2 receptors are a family of cell surface receptors that mediate a wide variety of physiologic effects in response to extracellular nucleotides. These receptors fall into two classes: P2X receptors, which are ligand-gated ion channels that mediate calcium and potassium fluxes in response to ATP, and P2Y receptors, which are G protein-coupled receptors (GPCRs). P2RX4 (P2X purinoceptor 4) is a receptor for ATP acting as a ligand gated ion channel.


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