PFKFB3 Monoclonal antibody

PFKFB3 Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

ELISA

Conjugate

Unconjugated

CloneNo.

4D1B11

Cat no : 60241-1-Ig

Synonyms



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 60241-1-Ig is PFKFB3 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen PFKFB3 fusion protein Ag4737
Full Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Calculated molecular weight 520 aa, 60 kDa
Observed molecular weight 55-58 kDa
GenBank accession numberBC040482
Gene symbol PFKFB3
Gene ID (NCBI) 5209
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5.