PFKFB3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60241-1-Ig |CloneNo.: 4D1B11

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Freight/Packing

Con: 225 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Calculated molecular weight:
520aa,60 kDa

Observed molecular weight:
55-58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PFKFB3

Synonyms
6PF 2 K/Fru 2,6 P2ase 3, FLJ37326, IPFK2, PFK/FBPase 3, PFK2, PFKFB3
Background

PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5.


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