ROCK2-Specific(C-term) Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 20248-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 52 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, mouse brain tissue

Positive IHC detected in:
human colon tissue, human brain tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
Rho-associated, coiled-coil containing protein kinase 2

Calculated molecular weight:
161 kDa

Observed molecular weight:
164 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ROCK2

Synonyms
KIAA0619, p164 ROCK 2, Rho kinase 2, ROCK2
Background

ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity (PMID:16574662).This antibody is specific to ROCK2.


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