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Secretogranin III Polyclonal antibody

Secretogranin III Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 10954-1-AP

Synonyms

SCG3, Secretogranin 3, secretogranin III, SGIII



Tested Applications

Positive IHC detected inmouse pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10954-1-AP targets Secretogranin III in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Secretogranin III fusion protein Ag1397
Full Name secretogranin III
Calculated molecular weight 53 kDa
GenBank accession numberBC014539
Gene symbol SCG3
Gene ID (NCBI) 29106
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Secretogranin III (SCG3), a member of the granin protein family, is expressed specifically in neuronal and endocrine cells. SCG3 was synthesized as a 61- or 63-kDa protein and processed to a 48-kDa form which, in turn, was partially cleaved to fragments of 28 and 20 kDa.

Protocols

Product Specific Protocols
IHC protocol for Secretogranin III antibody 10954-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

Exp Eye Res

Secretogranin III as a novel target for the therapy of choroidal neovascularization.

Authors - Michelle E LeBlanc
mouse

Exp Eye Res

Function-first ligandomics for ocular vascular research and drug target discovery.

Authors - Xin Rong
mouseIHC,IF

J Endocrinol

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

Authors - Hotta Kikuko K
human, mouseIHC

Brain Pathol

Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.

Authors - Virginia Plá
mouseWB,IHC

Cereb Cortex

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Authors - Paco Sonia S
humanWB,IHC

Cancer Lett

The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.

Authors - Yue Wang
  • KD Validated