EMAP II Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 11091-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
SGC-7901 cells, mouse pancreas tissue

Positive IHC detected in:
human cervical cancer tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)

Calculated molecular weight:
34 kDa

Observed molecular weight:
34kd and 68kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SCYE1

Synonyms
AIMP1, EMAP 2, EMAP II, EMAP2, EMAPII, p43, SCYE1
Background

SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34-kD precursor can be cleaved to produce an active 20-kD product(PMID:7929199). SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells(PMID:18292511). Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer(PMID:11306575).


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