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SOS1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55041-1-AP

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Con: 74 μg/150 μl

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Tested Applications
Applications:
ELISA, WB, IP, IF
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55041-1-AP;mouse brain tissue

mouse brain tissue were subjected to SDS PAGE followed by western blot with 55041-1-AP(SOS1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours

55041-1-AP;mouse brain tissue

IP Result of anti-SOS1 (IP:55041-1-AP, 4ug; Detection:55041-1-AP 1:500) with mouse brain tissue lysate 4000ug.

55041-1-AP;HeLa cells

Immunofluorescent analysis of HeLa cells using 55041-1-AP(SOS1 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG

Species specificity:
human, mouse, rat
Positive WB detected in:
mouse brain tissue, K-562 cells, mouse brain tissue
Positive IP detected in:
mouse brain tissue
Positive IF detected in:
HeLa cells
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Peptide
Full name:
son of sevenless homolog 1 (Drosophila)
Calculated molecular weight:
152 kDa
Observed molecular weight:
150 kDa
GenBank accession number:
NM_005633
Gene ID (NCBI):
6654
Gene symbol
SOS1
Synonyms
GF1, GGF1, GINGF, HGF, NS4, Son of sevenless homolog 1, SOS 1, SOS1
Background

SOS1 promotes the exchange of Ras-bound GDP by GTP. EPS8, E3B1 and SOS1 form a tricomplex in vivo that exhibits RAC-specific guanine nucleotide exchange factor activity in vitro. Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1). Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4). The antibody is specific to SOS1.


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