TRAIL Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 17235-1-AP

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human milk tissue, MCF-7 cells

Positive IP detected in:
A549 cells

Positive IHC detected in:
mouse liver tissue, human kidney tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
tumor necrosis factor (ligand) superfamily, member 10

Calculated molecular weight:
281aa,33 kDa

Observed molecular weight:
20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TNFSF10

Synonyms
Apo 2 ligand, Apo 2L, APO2L, CD253, Protein TRAIL, TL2, TNFSF10, TRAIL
Background

TRAIL is a 30 kD protein known as TNF-related apoptosis inducing ligand, CD253, TNFSF10, or Apo-2L. It is expressed as two kinds of forms: cell surface protein (30 kD) and soluble ligand (19-20 kD) produced by megakaryocytes and platelets, monocytes, neutrophils, NK cells and activated T cells. This antigen is also expressed on tumor cells and transformed cell lines. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process.


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