TRPV1 Antibody

TRPV1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat, mouse

Applications

IHC, WB, ELISA

Conjugate

Unconjugated

Publications

6

Cat no : 22686-1-AP

Synonyms

Capsaicin receptor, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1



Tested Applications

Positive WB detected inPC-12 cells
Positive IHC detected inhuman skin tissue, mouse skin tissue, human colon tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The 22686-1-AP immunogen is Fusion Protein TRPV1 protein expressed in E. coli.

Reactivity human, rat, mouse
Cited Species human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPV1 fusion protein Ag18583
Full Name transient receptor potential cation channel, subfamily V, member 1
Calculated molecular weight 839aa,95 kDa
Observed molecular weight 95 kDa
GenBank accession number BC132820
Gene symbol TRPV1
Gene ID (NCBI) 7442
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20oC. Aliquoting is unnecessary for -20oC storage.

Publications

SpeciesApplicationTitle
humanWB

Acta Pharmacol Sin

Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling.

Authors - Su-Shan Zhang
humanIF

Acta Otolaryngol

Expressions of TRPVs in the cholesteatoma epithelium.

Authors - Ba Hung Do
mouseWB

J Agric Food Chem

Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.

Authors - Shengnan Geng
mouseWB

Eur J Pharmacol

Spinophilin negatively controlled the function of transient receptor potential vanilloid 1 in dorsal root ganglia neurons of mice.

Authors - Zhen Guo
ratWB

Biomed Pharmacother

Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.

Authors - Weiwei Qin
mouseIHC

Oncotarget

Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice.

Authors - Jingjuan Hu