VPS16 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 17776-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells,HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
vacuolar protein sorting 16 homolog (S. cerevisiae)

Calculated molecular weight:
839aa,95 kDa

Observed molecular weight:
95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
VPS16

Synonyms
hVPS16, VPS16
Background

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. In yeast, Vps proteins are involved in the trafficking of endocytic and biosynthetic proteins to the vacuole, which functionally resembles the lysosome of higher organisms. Human VPS16 is the homolog of yeast class C Vps16 protein. VPS16 may play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.


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