ICAM-1/CD54 Monoklonaler Antikörper

ICAM-1/CD54 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2b, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

APC Fluorescent Dye

Publikationen(1)

CloneNo.

YN1/1.7.4

Kat-Nr. : APC-65066

Synonyme

CD54, Icam-1, ICAM 1, Icam1, MALA-2



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

FCSee 1 publications below

Produktinformation

APC-65066 bindet in FC ICAM-1/CD54 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Ratte / IgG2b, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Maus-NS-1-Zellen
Vollständiger Name intercellular adhesion molecule 1
GenBank-ZugangsnummerBC008626
Gene symbol ICAM-1
Gene ID (NCBI) 15894
Konjugation APC Fluorescent Dye
Excitation/Emission maxima wavelengths650 nm / 660 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.1% sodium azide and a stabilizer
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
FC protocol for APC ICAM-1/CD54 antibody APC-65066Download protocol
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseFC

Small

Long-Residence Pneumonia Vaccine Developed Using PEG-Grafted Hybrid Nanovesicles from Cell Membrane Fusion of Mycoplasma and IFN-γ-Primed Macrophages.

Authors - Zhenzhen Zhang