DLL1-Specific Polyklonaler Antikörper

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• KD/KO Validated

DLL1-Specific Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

5

Kat-Nr. : 20230-1-AP

Synonyme

Delta, delta like 1 (Drosophila), Delta like protein 1, DELTA1, DL1, DLL1, DLL1-Specific, Drosophila Delta homolog 1, H Delta 1

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Galerie der Validierungsdaten

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  WB analysis of human placenta using 20230-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse lung using 20230-1-AP

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Plazenta-Gewebe, Mauslungengewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 5 publications below

Produktinformation

20230-1-AP bindet in WB, ELISA DLL1-Specific und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: delta-like 1 (Drosophila)
• Berechnetes Molekulargewicht: 723 aa, 78 kDa
• Beobachtetes Molekulargewicht: 80 kDa
• GenBank-Zugangsnummer: NM_005618
• Gene symbol: DLL1
• Gene ID (NCBI): 28514
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DLL1, also named as Delta1, acts as a ligand for Notch receptors. DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. The antibody is specific to the protein DLL1.

Publikationen

Species	Application	Title
human	WB	Cell Rep; Transcriptional control of brain tumor stem cells by a carbohydrate binding protein; Authors - Ahmad Sharanek
human	WB	J Transl Med; MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia; Authors - Fanfan Li
human	WB	Int J Cancer; Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.; Authors - Qingmin Yuan
mouse	WB	Sci Rep; MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene.; Authors - Youguang Pu ; KD Validated
human	WB	Cell Death Dis; hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.; Authors - Xinxing Wan

Verwandte Produkte

NOTCH1 Polyclonal antibody

20687-1-AP

NOTCH3 Polyclonal antibody

55114-1-AP

Jagged 2 Polyclonal antibody

19696-1-AP

DLL4 Polyclonal antibody

21584-1-AP