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  • KD/KO Validated

ELK1 Polyklonaler Antikörper

ELK1 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14507-1-AP

Synonyme

ELK1



Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

KD/KOSee 1 publications below
WBSee 3 publications below

Produktinformation

14507-1-AP bindet in WB,ELISA ELK1 und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ELK1 fusion protein Ag5966
Vollständiger Name ELK1, member of ETS oncogene family
Berechnetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC056150
Gene symbol ELK1
Gene ID (NCBI) 2002
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

E twenty-six (ETS)-like transcription factor 1, also known as ELK1, is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. It is targeted in the nucleus by three major MAP kinase pathways as well as the CaMKII pathway. phosphorylation of nuclear Elk1 enhances its ability to bind DNA at serum response elements and stimulate transcription of immediate early genes. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer's disease, down syndrome, breast cancer, and depression. This antibody got an 62 kd band in western blotting maybe duo to its phosphorylation

Publikationen

SpeciesApplicationTitle
humanWB

Br J Pharmacol

L-Hcy-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinemia.

Authors - Yi-Ping Leng
humanWB

Gene

Competitive regulation of IPO4 transcription by ELK1 and GABP.

Authors - Pengpeng Xu
  • KD Validated
humanWB

Oncol Lett

MicroRNA-326 suppresses the proliferation, migration and invasion of cervical cancer cells by targeting ELK1.

Authors - Ping Zhang