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LAMP2 Polyklonaler Antikörper

LAMP2 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (2)

Anwendung

IHC, IF, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10397-1-AP

Synonyme

CD107b, LAMP 2, LAMP2, LAMPB, LGP110

Galerie der Validierungsdaten

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  • Immunohistochemistry (IHC) staining of human placenta tissue using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IHC staining of human placenta using 10397-1-AP

    Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human placenta tissue using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IHC staining of human placenta using 10397-1-AP

    Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human skeletal muscle tissue using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IHC staining of human skeletal muscle using 10397-1-AP

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IHC staining of human pancreas cancer using 10397-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IHC staining of human pancreas cancer using 10397-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IF Staining of HepG2 using 10397-1-AP

    Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using CD107b / LAMP2 Polyclonal antibody (10397-1-AP)

    IF Staining of HepG2 using 10397-1-AP

    Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

IHCSee 3 publications below
IFSee 6 publications below

Produktinformation

10397-1-AP bindet in IHC, IF, ELISA LAMP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte Reaktivitäthuman, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen LAMP2 fusion protein Ag0595
Vollständiger Name lysosomal-associated membrane protein 2
Berechnetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC002965
Gene symbol LAMP2
Gene ID (NCBI) 3920
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.

Publikationen

SpeciesApplicationTitle
humanIF

Oxid Med Cell Longev

The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.

Authors - Jinhua Wu
View Article
human

Cell Death Dis

Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.

Authors - L Zhang
View Article
humanIF

Acta Neuropathol Commun

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.

Authors - Petra Frick
View Article
mouseIF

Sci Rep

Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.

Authors - Takeshi Into
View Article
mouse

Biomedicines

IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.

Authors - Yong-Shiou Lin
View Article
mouseIF

Front Pharmacol

Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.

Authors - Jiao Zhou
View Article