LYVE1 Polyklonaler Antikörper

LYVE1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

7

Kat-Nr. : 51011-1-AP

Synonyme

CRSBP 1, CRSBP1, HAR, Hyaluronic acid receptor, LYVE 1, LYVE1, XLKD1

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Galerie der Validierungsdaten

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  WB analysis of human brain using 51011-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HUVEC-Zellen, bEnd.3-Zellen, humanes Hirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Produktinformation

51011-1-AP bindet in WB, IHC, IF, ELISA LYVE1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LYVE1 fusion protein Ag0570
• Vollständiger Name: lymphatic vessel endothelial hyaluronan receptor 1
• Berechnetes Molekulargewicht: 322 aa, 35 kDa
• Beobachtetes Molekulargewicht: 60-70 kDa
• GenBank-Zugangsnummer: BC026231
• Gene symbol: LYVE1
• Gene ID (NCBI): 10894
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LYVE1 is a 322-amino acid type-I integral membrane glycoprotein primarily expressed on lymphatic endothelial cells. LYVE1 is a CD44 homologue. It acts as a receptor and binds to both soluble and immobilized hyaluronan. LYVE1 may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

Publikationen

Species	Application	Title
mouse	IHC	Cell Rep; Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy; Authors - Qicong Luo
human		Cell Death Dis; PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.; Authors - Xin Liang
human,mouse	WB,IHC	Biomedicines; Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.; Authors - Hsien-Lin Chen
mouse	IF	Front Physiol; Endothelial Microparticle-Mediated Transfer of microRNA-19b Inhibits the Function and Distribution of Lymphatic Vessels in Atherosclerotic Mice.; Authors - Shi-Ran Yu
mouse	IHC	Ann Transl Med; Clostridium butyricum alleviates dextran sulfate sodium-induced experimental colitis and promotes intestinal lymphatic vessel regeneration in mice.; Authors - Xing Chen
human	WB	Biol Pharm Bull; Establishment and characterization of a human lymphatic endothelial cell line.; Authors - Ryosuke Nakamura