RAB20 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

RAB20 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

4

Kat-Nr. : 11616-1-AP

Synonyme

RAB20, Ras related protein Rab 20

---

Galerie der Validierungsdaten

• 

---

Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 3 publications below
• WB: See 4 publications below
• IF: See 4 publications below

Produktinformation

11616-1-AP bindet in WB, IF, ELISA RAB20 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RAB20 fusion protein Ag2193
• Vollständiger Name: RAB20, member RAS oncogene family
• Berechnetes Molekulargewicht: 26 kDa
• Beobachtetes Molekulargewicht: 26-29 kDa
• GenBank-Zugangsnummer: BC026025
• Gene symbol: RAB20
• Gene ID (NCBI): 55647
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAB20 is a member of RAS oncogene family, it has no close relationship to any other members of RAB subfamily which consists of small GTP-binding proteins involved in the regulation of intracellullar vesicular transport. Firstly found highly expressed on the apical side of kidney tubuel epithelial cells, RAB20 was speculated to be involved in apical endocytosi and recylcing processes. So far, its function is not well known, however, RAB20 is recently found higher expressed in pancreatic adenocarcinomas than normal pancreas, which is proved by WB and IHC analyses, suggesting its promising role in diagnosis of pancreatic carcinogenesis. Catalog#11616-1-AP is a rabbit polyclonal antibody raised against full-length of human RAB20.

Publikationen

Species	Application	Title
mouse	WB,IF	Cell Host Microbe; A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.; Authors - Laura Schnettger ; KO Validated
mouse	WB,IF	J Cell Sci; Identification of an immune-regulated phagosomal Rab cascade in macrophages.; Authors - Gang Pei ; KD Validated
mouse	WB,IF	Mol Biol Cell; Interferon-gamma-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages.; Authors - Gang Pei ; KD Validated
mouse	IF,WB	Front Mol Neurosci; Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction; Authors - Jia Guo