Anticorps Monoclonal anti-CD40

CD40 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Fluorescent Dye

Publications(4)

CloneNo.

1C10

N° de cat : FITC-65062

Synonymes

Bp50, CD40 antigen, Tnfrsf5



Applications testées

Résultats positifs en cytométriesplénocytes de souris BALB/c,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

FCSee 4 publications below

Informations sur le produit

FITC-65062 cible CD40 dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Réactivité citéesouris
Hôte / Isotype Rat / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène sCD40
Nom complet CD40 antigen
Numéro d’acquisition GenBankBC029254
Symbole du gène Cd40
Identification du gène (NCBI) 21939
Conjugaison FITC Fluorescent Dye
Excitation/Emission maxima wavelengths494 nm / 520 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497).

Protocole

Product Specific Protocols
FC protocol for FITC CD40 antibody FITC-65062Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseFC

Int Immunopharmacol

Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy

Authors - Xu Gao
mouseFC

Adv Healthc Mater

Pathogen-mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Iimmunization

Authors - Hongping Wan
mouseFC

Int J Biol Macromol

Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization

Authors - Kai Deng
mouseFC

Int Immunopharmacol

Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2

Authors - Xu Gao
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