Anticorps Polyclonal de lapin anti-DLL1-Specific

• Phare
• Validé par KD/KO

DLL1-Specific Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications(5)

N° de cat : 20230-1-AP

Synonymes

Delta, delta like 1 (Drosophila), Delta like protein 1, DELTA1, DL1, DLL1, DLL1-Specific, Drosophila Delta homolog 1, H Delta 1

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Galerie de données de validation

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  WB analysis of human placenta using 20230-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse lung using 20230-1-AP

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu placentaire humain, tissu pulmonaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 5 publications below

Informations sur le produit

20230-1-AP cible DLL1-Specific dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: delta-like 1 (Drosophila)
• Masse moléculaire calculée: 723 aa, 78 kDa
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: NM_005618
• Symbole du gène: DLL1
• Identification du gène (NCBI): 28514
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

DLL1, also named as Delta1, acts as a ligand for Notch receptors. DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. The antibody is specific to the protein DLL1.

Publications

Species	Application	Title
human	WB	Cell Rep; Transcriptional control of brain tumor stem cells by a carbohydrate binding protein; Authors - Ahmad Sharanek
human	WB	J Transl Med; MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia; Authors - Fanfan Li
human	WB	Int J Cancer; Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.; Authors - Qingmin Yuan
mouse	WB	Sci Rep; MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene.; Authors - Youguang Pu ; KD Validated
human	WB	Cell Death Dis; hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.; Authors - Xinxing Wan

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