Anticorps Polyclonal de lapin anti-LAMP2

LAMP2 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (2)

Applications

IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

18

N° de cat : 10397-1-AP

Synonymes

CD107b, LAMP 2, LAMP2, LAMPB, LGP110

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Galerie de données de validation

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  IHC staining of human placenta using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human placenta using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human skeletal muscle using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human pancreas cancer using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human pancreas cancer using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IF Staining of HepG2 using 10397-1-AP

  Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

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  IF Staining of HepG2 using 10397-1-AP

  Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 3 publications below
• IF: See 6 publications below

Informations sur le produit

10397-1-AP cible LAMP2 dans les applications de IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LAMP2 Protéine recombinante Ag0595
• Nom complet: lysosomal-associated membrane protein 2
• Masse moléculaire calculée: 45 kDa
• Numéro d’acquisition GenBank: BC002965
• Symbole du gène: LAMP2
• Identification du gène (NCBI): 3920
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.

Publications

Species	Application	Title
human	IF	Oxid Med Cell Longev; The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.; Authors - Jinhua Wu
human		Cell Death Dis; Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.; Authors - L Zhang
human	IF	Acta Neuropathol Commun; Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.; Authors - Petra Frick
mouse	IF	Sci Rep; Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.; Authors - Takeshi Into
mouse		Biomedicines; IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.; Authors - Yong-Shiou Lin
mouse	IF	Front Pharmacol; Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.; Authors - Jiao Zhou

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