Anticorps Polyclonal de lapin anti-LYVE1

LYVE1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

7

N° de cat : 51011-1-AP

Synonymes

CRSBP 1, CRSBP1, HAR, Hyaluronic acid receptor, LYVE 1, LYVE1, XLKD1

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Galerie de données de validation

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  WB analysis of human brain using 51011-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 51011-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 51011-1-AP (LYVE1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HUVEC, cellules bEnd.3, tissu cérébral humain

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Informations sur le produit

51011-1-AP cible LYVE1 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LYVE1 Protéine recombinante Ag0570
• Nom complet: lymphatic vessel endothelial hyaluronan receptor 1
• Masse moléculaire calculée: 322 aa, 35 kDa
• Poids moléculaire observé: 60-70 kDa
• Numéro d’acquisition GenBank: BC026231
• Symbole du gène: LYVE1
• Identification du gène (NCBI): 10894
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

LYVE1 is a 322-amino acid type-I integral membrane glycoprotein primarily expressed on lymphatic endothelial cells. LYVE1 is a CD44 homologue. It acts as a receptor and binds to both soluble and immobilized hyaluronan. LYVE1 may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

Publications

Species	Application	Title
mouse	IHC	Cell Rep; Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy; Authors - Qicong Luo
human		Cell Death Dis; PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.; Authors - Xin Liang
human,mouse	WB,IHC	Biomedicines; Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.; Authors - Hsien-Lin Chen
mouse	IF	Front Physiol; Endothelial Microparticle-Mediated Transfer of microRNA-19b Inhibits the Function and Distribution of Lymphatic Vessels in Atherosclerotic Mice.; Authors - Shi-Ran Yu
mouse	IHC	Ann Transl Med; Clostridium butyricum alleviates dextran sulfate sodium-induced experimental colitis and promotes intestinal lymphatic vessel regeneration in mice.; Authors - Xing Chen
human	WB	Biol Pharm Bull; Establishment and characterization of a human lymphatic endothelial cell line.; Authors - Ryosuke Nakamura