Anticorps Polyclonal de lapin anti-RAB20

• Phare
• Validé par KD/KO

RAB20 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications

4

N° de cat : 11616-1-AP

Synonymes

RAB20, Ras related protein Rab 20

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Galerie de données de validation

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 3 publications below
• WB: See 4 publications below
• IF: See 4 publications below

Informations sur le produit

11616-1-AP cible RAB20 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RAB20 Protéine recombinante Ag2193
• Nom complet: RAB20, member RAS oncogene family
• Masse moléculaire calculée: 26 kDa
• Poids moléculaire observé: 26-29 kDa
• Numéro d’acquisition GenBank: BC026025
• Symbole du gène: RAB20
• Identification du gène (NCBI): 55647
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

RAB20 is a member of RAS oncogene family, it has no close relationship to any other members of RAB subfamily which consists of small GTP-binding proteins involved in the regulation of intracellullar vesicular transport. Firstly found highly expressed on the apical side of kidney tubuel epithelial cells, RAB20 was speculated to be involved in apical endocytosi and recylcing processes. So far, its function is not well known, however, RAB20 is recently found higher expressed in pancreatic adenocarcinomas than normal pancreas, which is proved by WB and IHC analyses, suggesting its promising role in diagnosis of pancreatic carcinogenesis. Catalog#11616-1-AP is a rabbit polyclonal antibody raised against full-length of human RAB20.

Publications

Species	Application	Title
mouse	WB,IF	Cell Host Microbe; A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.; Authors - Laura Schnettger ; KO Validated
mouse	WB,IF	J Cell Sci; Identification of an immune-regulated phagosomal Rab cascade in macrophages.; Authors - Gang Pei ; KD Validated
mouse	WB,IF	Mol Biol Cell; Interferon-gamma-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages.; Authors - Gang Pei ; KD Validated
mouse	IF,WB	Front Mol Neurosci; Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction; Authors - Jia Guo