Tested Applications
| Positive WB detected in | SMMC-7721 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
18734-1-AP targets HOXD11 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | homeobox D11 |
| Calculated Molecular Weight | 35 kDa |
| Observed Molecular Weight | 32-36 kDa |
| GenBank Accession Number | BC160135 |
| Gene Symbol | HOXD11 |
| Gene ID (NCBI) | 3237 |
| RRID | AB_2878558 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P31277 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
HOXD11, also named as HOX4F, belongs to the Abd-B homeobox family. HOXD11 is a sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. HOXD11 plays a role in forelimb morphogenesis.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for HOXD11 antibody 18734-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The HOXD11 Polyclonal antibody (Cat# 18734-1-AP) has 7 citations published in journals including Cell Stem Cell, Cancer Research, Cell Reports, J Orthop Surg Res, Mol Biotechnol, and Discov Oncol. Research fields span kidney organoid generation, hepatocellular tumor stem cell retrodifferentiation, chromatin regulation in embryonic stem cells, neuroendocrine prostate cancer, osteoarthritis/cartilage degradation, laryngeal squamous cell carcinoma, and colorectal cancer progression.
| Species | Application | Title |
|---|---|---|
Cell Stem Cell Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. | ||
Cancer Res Retrodifferentiation of human tumor hepatocytes to stem cells leads to metabolic reprogramming and chemoresistance. | ||
Cell Rep HOXD11-NMDAR signaling drives neuroendocrine prostate cancer and enables potential therapeutic intervention as a target of memantine.
| ||
J Orthop Surg Res Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development | ||
Mol Biotechnol CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis |
