Tested Applications
| Positive WB detected in | mouse cerebellum tissue, 786-O cells, ACHN cells, PANC-1 cells, rat cerebellum tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
29307-1-AP targets PAX2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag30717 Product name: Recombinant human PAX2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 189-386 aa of BC148710 Sequence: GILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRF Predict reactive species |
| Full Name | paired box 2 |
| Calculated Molecular Weight | 431 aa, 46 kDa |
| Observed Molecular Weight | 45 kDa |
| GenBank Accession Number | BC148710 |
| Gene Symbol | PAX2 |
| Gene ID (NCBI) | 5076 |
| RRID | AB_2918278 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q02962 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PAX2 is a transcription factor, primarily expressed during embryonic development. It has a critical role in the development of the urogenital tract, the eyes, and the CNS. It plays a key role during renal development and to act as an oncogene favoring renal tumor growth. PAX2 was suggested as a sensitive and highly specific marker for renal cell carcinoma (RCC).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for PAX2 antibody 29307-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The PAX2 Polyclonal antibody (Cat# 29307-1-AP) has 6 total citations. These appear in Sci Bull (Beijing), Cells, Sci Rep, J Cell Mol Med, Exp Ther Med, and Angiogenesis. Research fields span ovarian cancer reprogramming, renal cell maturation and regenerative therapies, retinal angiogenesis, endometrial dysfunction, appendiceal mucinous tumour pathology, and murine renal vascular development.
| Species | Application | Title |
|---|---|---|
Sci Bull (Beijing) Reprogramming of Ovarian Granulosa Cells by YAP1 Leads to Development of High-Grade Cancer with Mesenchymal Lineage and Serous Features. | ||
Cells Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies. | ||
Sci Rep Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions. | ||
J Cell Mol Med Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic Analysis | ||
Exp Ther Med Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review. | ||
Angiogenesis Zonal endothelial cell heterogeneity underlies murine renal vascular development. |
