CD74 Recombinant antibody

CD74 Uni-rAbTM Recombinant Antibody for IHC, ELISA
Cat No. 85802-2-RR
Clone No.250109B11

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

IHC, ELISA

Class-II-associated invariant chain peptide, CLIP, H-2 class II histocompatibility antigen gamma chain, Ia antigen-associated invariant chain, Ii

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive IHC detected inmouse spleen tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:2000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

85802-2-RR targets CD74 in IHC, ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CD74 fusion protein Eg2716 Predict reactive species
Full Name CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Calculated Molecular Weight32 kDa
GenBank Accession NumberNM_001042605.1
Gene Symbol Cd74
Gene ID (NCBI) 16149
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP04441-1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165; PMID: 36712241).

Protocols

Product Specific Protocols
IHC protocol for CD74 antibody 85802-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...