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NPRC/NPR3 Recombinant monoclonal antibody

NPRC/NPR3 Uni-rAb® Recombinant Antibody for WB, ELISA

Cat No. 86206-1-RR
Clone No.250746C4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

NPR3, ANP C, ANP-C, ANPR C, ANPRC

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 
SKU: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

86206-1-RR targets NPRC/NPR3 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen

CatNo: Eg2988

Product name: Recombinant Human NPRC/NPR3 protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 27-481 aa of NM_001204375.2

Sequence: GGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEE

Predict reactive species
Full Name natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Calculated Molecular Weight60 kDa
Observed Molecular Weight 60-70 kDa
GenBank Accession NumberNM_001204375.2
Gene Symbol NPR3
Gene ID (NCBI) 4883
RRIDAB_3744716
Conjugate Unconjugated
FormLiquid
Purification MethodProtein A purification
UNIPROT IDP17342-1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor. The family of natriuretic peptides elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. NPR3 has 3 isoforms with MWs of 37~60 kDa produced by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for NPRC/NPR3 antibody 86206-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

SpeciesApplicationTitle
humanWB

Biochim Biophys Acta Gen Subj

NPR3 promotes colorectal cancer cell proliferation, migration, invasion, and chemotherapy resistance.

Authors - Wensheng Chen
  • KD Validated
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