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Tested Applications
| Positive WB detected in | mouse heart tissue, rat heart tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87491-1-RR targets GPR15 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | G protein-coupled receptor 15 |
| Calculated Molecular Weight | 360 aa, 41 kDa |
| Observed Molecular Weight | 40 kDa |
| GenBank Accession Number | BC101779 |
| Gene Symbol | GPR15 |
| Gene ID (NCBI) | 2838 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P49685 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
GPR15 is a Gi-coupled GPCR that directs T cell homing to the colon, playing a central role in mucosal immune surveillance and intestinal homeostasis. Through recognition of GPR15L, GPR15 regulates lymphocyte migration and inflammatory tone within the gut. Dysregulation of this axis contributes to inflammatory bowel disease, autoimmune pathology, and altered tumor immune landscapes, highlighting GPR15 as a key mediator of tissue-specific immune trafficking.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for GPR15 antibody 87491-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
