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Tested Applications
| Positive IF/ICC detected in | THP-1 cells |
| Positive FC detected in | U2OS cells, THP-1 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
98650-1-RR targets MCOLN2 in IF/ICC, FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | mucolipin 2 |
| Calculated Molecular Weight | 566 aa, 66 kDa |
| GenBank Accession Number | BC104891 |
| Gene Symbol | MCOLN2 |
| Gene ID (NCBI) | 255231 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q8IZK6 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
MCOLN2 (Mucolipin-2), also known as TRPML2, is a member of the transient receptor potential mucolipin (TRPML) family of gated cation channels. Primarily localized in the membranes of endosomes and lysosomes, it plays critical roles in intracellular trafficking, immune responses, and disease progression
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for MCOLN2 antibody 98650-1-RR | Download protocol |
| IF protocol for MCOLN2 antibody 98650-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
