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Anti-Human CCR7 Rabbit Recombinant Antibody (98717-1-RR)

Anti-Human CCR7 Rabbit Recombinant Antibody

CCR7 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98717-1-RR

Clone No.253310A1

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

BLR2, C C chemokine receptor type 7, C C CKR 7, C-C chemokine receptor type 7, CC CKR 7

Formulation: PBS, Azide

PBS, Azide

PBS Only

Conjugate: Unconjugated

Unconjugated

Size/Concentration:

SKU:

-/ -

Freight/Packing: -

Quantity

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Filter: AllFC

FC experiment of human PBMCs using 98717-1-RR
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with FITC Plus Anti-Human CD45RA. CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
FC experiment of human PBMCs using 98717-1-RR
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Overview

Tested Applications
Product Information
Protocols

Print datasheet

MSDS SDS

Tested Applications

Positive FC detected in

human PBMCs

Recommended dilution

Application	Dilution
Flow Cytometry (FC)	FC : 0.25 ug per 10^6 cells in a 100 µl suspension
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98717-1-RR targets CCR7 in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	unknow Predict reactive species
Full Name	chemokine (C-C motif) receptor 7
Gene Symbol	CCR7
Gene ID (NCBI)	1236
RRID	AB_3746296
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P32248
Storage Buffer	PBS with 0.09% sodium azide, pH 7.3.
Storage Conditions	Store at 2 - 8°C. Stable for one year after shipment.

Background Information

C-C chemokine receptor type 7 (CCR7), which belongs to the G-protein coupled receptor 1 family, is also a receptor for the MIP-3-beta chemokine, and probably acts as a mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. CCR7 is specially expressed in various lymphoid tissues and activated B- and T-lymphocytes, and can be strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.