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Anti-Human CCR7 Rabbit Recombinant Antibody, PBS Only (98717-1-PBS)

Anti-Human CCR7 Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human CCR7 Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98717-1-PBS-1MG

CCR7 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98717-1-PBS

Clone No.253310A1

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

BLR2, C C chemokine receptor type 7, C C CKR 7, C-C chemokine receptor type 7, CC CKR 7

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

Size/Concentration:

SKU:

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Filter: AllFC

FC experiment of human PBMCs using 98717-1-RR (same clone as 98717-1-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with FITC Plus Anti-Human CD45RA. CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98717-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with FITC Plus Anti-Human CD45RA. CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98717-1-PBS in a different storage buffer formulation.
FC experiment of human PBMCs using 98717-1-RR (same clone as 98717-1-PBS)
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98717-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CCR7 Rabbit RecAb (98717-1-RR, Clone: 253310A1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). CD4+ cells were gated. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98717-1-PBS in a different storage buffer formulation.

Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98717-1-PBS targets CCR7 in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	unknow Predict reactive species
Full Name	chemokine (C-C motif) receptor 7
Gene Symbol	CCR7
Gene ID (NCBI)	1236
RRID	AB_3746296
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P32248
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

C-C chemokine receptor type 7 (CCR7), which belongs to the G-protein coupled receptor 1 family, is also a receptor for the MIP-3-beta chemokine, and probably acts as a mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. CCR7 is specially expressed in various lymphoid tissues and activated B- and T-lymphocytes, and can be strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.