Recombinant Mouse IGFBP1 protein (rFc Tag)(HPLC verified)

Species

Mouse

Purity

>90 %, SDS-PAGE
>90 %, SEC-HPLC

Tag

rFc Tag

Activity

not tested

Cat no : Eg2934



Product Information

Purity >90 %, SDS-PAGE
>90 %, SEC-HPLC
Endotoxin <0.1 EU/μg protein, LAL method
Activity
Not tested
Expression HEK293-derived Mouse IGFBP1 protein Ala26-Asn272 (Accession# P47876) with a rabbit IgG Fc tag at the C-terminus.
GeneID 16006
Accession P47876
PredictedSize 52.9 kDa
SDS-PAGE 52-60 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

IGFBP1 is a binding protein that is produced primarily by the liver outside of pregnancy and is highly expressed by the placenta. IGFBP1 has been implicated in the modulation of the biological activity of insulin-like growth factor (IGF)-1 and IGF-2, which are key regulators of growth and metabolism in postnatal and fetal life.

References:

1. Uhlén M, et al. (2015). Science. ;347:1260419. 2. Duan C, et al. (2005). Comp. Endocrinol. ;142:44–52.

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