Recombinant Human SDC4 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg6782
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human SDC4 protein Glu19-Glu145 (Accession# P31431-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 6385 |
| Accession | P31431-1 |
| PredictedSize | 39.9 kDa |
| SDS-PAGE | 46-50 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
SDC4, also known as syndecan 4, is a cell surface proteoglycan that bears heparan sulfate, which is involved in normal wound healing. It has been reported that SDC4 may be associated with keratinocyte proliferation and differentiation in the epidermis. SDC4 also plays a key role in angiogenesis and inflammation.
References:
1.Carvallo, Loreto et al. The Journal of biological chemistry vol. 285,38 (2010): 29546-55. 2.Chen, Liang-Liang et al. Molecules and cells vol. 41,9 (2018): 853-867. 3.Cai, Peian et al. Journal of cellular physiology vol. 235,2 (2020): 1746-1758.