Product Information
22216-1-PBS targets ADAM19 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag17544 Product name: Recombinant human ADAM19 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 291-471 aa of BC024214 Sequence: YYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESSRRPPPSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPGAGPQQSRPLAALAPK Predict reactive species |
| Full Name | ADAM metallopeptidase domain 19 (meltrin beta) |
| Calculated Molecular Weight | 955 aa, 105 kDa |
| Observed Molecular Weight | 105 kDa |
| GenBank Accession Number | BC024214 |
| Gene Symbol | ADAM19 |
| Gene ID (NCBI) | 8728 |
| RRID | AB_2879034 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H013 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Meltrinβ(ADAM19) is a metalloprotease-disintegrin expressed in the peripheral nervous system and other organs during embryogenesis. Its specific patterns of expression during embryogenesis suggest that it is involved in the development of the peripheral nervous system, skeletal muscle, bone and heart tissue(PMID:12482604). It participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.
