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ADRP/Perilipin 2 Polyclonal antibody

ADRP/Perilipin 2 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (5)





Cat no : 15294-1-AP


ADFP, Adipophilin, ADRP, ADRP/Perilipin 2, Perilipin 2, PLIN2

Tested Applications

Positive WB detected inmouse liver tissue, K-562 cells, rat liver tissue, NIH/3T3 cells
Positive IHC detected inhuman liver cancer tissue, mouse liver tissue, human liver tissue, human renal cell carcinoma tissue, human prostate cancer tissue, human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inoleic acid treated HeLa cells

Recommended dilution

Western Blot (WB)WB : 1:2000-1:16000
Immunohistochemistry (IHC)IHC : 1:200-1:8000
Immunofluorescence (IF)IF : 1:200-1:800
Sample-dependent, check data in validation data gallery

Product Information

15294-1-AP targets ADRP/Perilipin 2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, monkey, zebrafish, pig, canine, bovine
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADRP/Perilipin 2 fusion protein Ag7539
Full Name adipose differentiation-related protein
Calculated molecular weight 48 kDa
Observed molecular weight 45-48 kDa
GenBank accession numberBC005127
Gene symbol ADFP
Gene ID (NCBI) 123
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ADRP (adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.


Product Specific Protocols
WB protocol for ADRP/Perilipin 2 antibody 15294-1-APDownload protocol
IHC protocol for ADRP/Perilipin 2 antibody 15294-1-APDownload protocol
IF protocol for ADRP/Perilipin 2 antibody 15294-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle.

Authors - Simona Ricciardi

Cell Metab

Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.

Authors - Yi Fu

Nat Commun

Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy

Authors - Donghai Cui

Mol Cell

Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.

Authors - Anyuan He

Nat Commun

O-GlcNAc transferase inhibits visceral fat lipolysis and promotes diet-induced obesity.

Authors - Yunfan Yang

Cell Death Differ

Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation.

Authors - Yi Wu


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Christine (Verified Customer) (09-19-2023)

Tried on HEK293T cells treated with 300 uM oleic acid overnight to induce the formation of lipid droplets. This antibody decorates some droplets but was a bit weak. TIP47 antibody (10694-1-AP) performed better (clearer detection of the droplets) at the same concentration (1:100).

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: HEK293T

Kamal (Verified Customer) (07-05-2023)

Worked well when diluted with 1X PBS.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:200
  • Cell Tissue Type: Mouse Liver tissue

Christin (Verified Customer) (03-09-2023)

Great antibody for WB with low background signal.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: human iPSC-derived microglia and macrophages

Nick (Verified Customer) (04-20-2022)

Helped localize expression of Plin2

  • Applications: Western Blot, Immunoprecipitation, Cell culture
  • Cell Tissue Type: 3T3-L1

Boyan (Verified Customer) (05-09-2019)

Very good for WB

  • Applications: Western Blot,
  • Cell Tissue Type: MEF