AGER/RAGE Recombinant antibody

• 

  WB analysis of mouse lung using 85349-1-RR

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 85349-1-RR (AGER antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of pig lung using 85349-1-RR

  pig lung tissue were subjected to SDS PAGE followed by western blot with 85349-1-RR (AGER antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

AGER/RAGE Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 85349-1-RR

Clone No.242714G12

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, pig

Applications

WB, ELISA

Synonyms

AGER, RAGE, 242714G12, Advanced glycosylation end product-specific receptor

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Tested Applications

• Positive WB detected in: mouse lung tissue, pig lung tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

85349-1-RR targets AGER/RAGE in WB, ELISA applications and shows reactivity with human, mouse, pig samples.

• Tested Reactivity: human, mouse, pig
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: AGER/RAGE fusion protein Eg3860
• Full Name: advanced glycosylation end product-specific receptor
• Calculated Molecular Weight: 404 aa, 43 kDa
• Observed Molecular Weight: 43 kDa
• GenBank Accession Number: BC020669
• Gene Symbol: AGER
• Gene ID (NCBI): 177
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q15109
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The receptor for advanced glycation end products (RAGE) is a cell surface transmembrane multiligand receptor, also known as Ager, is a multiligand member of the immunoglobulin superfamily. It has many isoforms and is predominantly expressed in the lung. AGER expression is upregulated in many diseases such as Alzheimer's disease, diabetes mellitus, atherosclerosis, and rheumatoid arthritis (PMID: 35099614).