AKAP1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15618-1-AP

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Freight/Packing

Con: 36 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
HeLa cells, human liver tissue, MCF-7 cells, PC-3 cells

Positive IP detected in:
PC-3 cells

Positive IHC detected in:
human colon cancer tissue, human colon cancer tissue, human prostate cancer tissue, human small intestine tissue

Positive IF detected in:
MCF-7 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
A kinase (PRKA) anchor protein 1

Calculated molecular weight:
97 kDa

Observed molecular weight:
149 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AKAP1

Synonyms
AKAP, AKAP 149, AKAP1, AKAP121, AKAP149, AKAP84, D AKAP 1, D AKAP1, PRKA1, S AKAP84, SAKAP84
Background

AKAP1 (also termed AKAP149) is a human 149 kDa anchoring protein localized in mitochondria and the endoplasmic reticulum/nuclear envelope (ER-NE) network. It Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.


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