ALDH1B1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22220-1-AP

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Freight/Packing

Con: 87 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HepG2 cells, mouse brain tissue, mouse testis tissue, rat brain tissue

Positive IHC detected in:
human testis tissue, human liver tissue, human testis tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aldehyde dehydrogenase 1 family, member B1

Calculated molecular weight:
517aa,57 kDa

Observed molecular weight:
55-58 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALDH1B1

Synonyms
Aldehyde dehydrogenase 5, ALDH1B1, ALDH5, ALDHX
Background

Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.(PMID:21216231). ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung(PMID:18611112). This antibody is specific to ALDH1B1.


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