ALOX5 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66326-1-Ig |CloneNo.: 3B1B7

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Con: 150 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
pig spleen tissue

Positive IHC detected in:
human lung tissue, human lung tissue, human spleen tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:100-1:400

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
arachidonate 5-lipoxygenase

Calculated molecular weight:
674aa,78 kDa

Observed molecular weight:
78 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALOX5

Synonyms
5 lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, arachidonate 5 lipoxygenase, LOG5
Background

ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).


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