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  • KD/KO Validated

Annexin A11 Polyclonal antibody

Annexin A11 Polyclonal Antibody for WB, IP, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 10479-2-AP


56 kDa autoantigen, Annexin 11, annexin A11, Annexin XI, ANX11, ANXA11, CAP 50, CAP50

Tested Applications

Positive WB detected inHeLa cells, mouse uterus tissue
Positive IP detected inHeLa cells
Positive IHC detected inhuman ovary tumor tissue, human breast cancer tissue, human kidney tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHeLa cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10479-2-AP targets Annexin A11 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Annexin A11 fusion protein Ag0729
Full Name annexin A11
Calculated Molecular Weight 56 kDa
Observed Molecular Weight 56-60 kDa
GenBank Accession NumberBC007564
Gene Symbol ANXA11
Gene ID (NCBI) 311
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Annexin A11 (Anxa11) is one member of annexins that are Ca2+-regulated phospholipid-binding proteins. Annexin A11 plays an important role in cell division, differentiation, apoptosis, vesicle trafficking and Ca2+ signaling. Annexin A11 dysregulation is involved in the progression, drug-resistance, recurrence of systemic autoimmune disease and cancer.


Product Specific Protocols
WB protocol for Annexin A11 antibody 10479-2-APDownload protocol
IHC protocol for Annexin A11 antibody 10479-2-APDownload protocol
IF protocol for Annexin A11 antibody 10479-2-APDownload protocol
IP protocol for Annexin A11 antibody 10479-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Sci Transl Med

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Authors - Bradley N Smith

Ann Neurol

A Novel Multisystem Proteinopathy Caused by a Missense ANXA11 Variant.

Authors - Tauana Bernardes Leoni


ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun.

Authors - Shuqing Liu
  • KD Validated

Biomed Pharmacother

Annexin A11 knockdown inhibits in vitro proliferation and enhances survival of Hca-F cell via Akt2/FoxO1 pathway and MMP-9 expression.

Authors - Shuqing Liu
  • KD Validated

Neurobiol Aging

Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis.

Authors - Elisa Teyssou

Ann Clin Transl Neurol

Adult-onset dominant muscular dystrophy in Greek families caused by Annexin A11

Authors - Mridul Johari