ANXA2R Polyclonal antibody, PBS Only

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• ANXA2R Polyclonal antibody, PBS Only (23838-1-PBS)

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  IHC staining of human prostate cancer using 23838-1-AP (same clone as 23838-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 23838-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 23838-1-AP (same clone as 23838-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 23838-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 23838-1-AP (same clone as 23838-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 23838-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 23838-1-AP (same clone as 23838-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 23838-1-PBS in a different storage buffer formulation.

ANXA2R Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 23838-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Synonyms

C5orf39, Annexin 2 receptor, Annexin II receptor, Annexin-2 receptor, AX2R

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Product Information

23838-1-PBS targets ANXA2R in IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag20807

  Product name: Recombinant human C5orf39 protein

  Source: e coli.-derived, PET30a

  Tag: 6*His

  Domain: 1-193 aa of BC067873

  Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLRQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP

• Full Name: chromosome 5 open reading frame 39
• Calculated Molecular Weight: 193 aa, 22 kDa
• GenBank Accession Number: BC067873
• Gene Symbol: ANXA2R
• Gene ID (NCBI): 389289
• RRID: AB_2879333
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: Q3ZCQ2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ANXA2R (annexin A2 receptor) is a receptor protein that interacts with annexin A2 (ANXA2). ANXA2R plays significant roles in various diseases. For instance, in renal cell carcinoma (RCC), high expression of ANXA2R is associated with poor prognosis. A recent study published in Nature revealed that SP140 regulates interferon mRNA stability and antiviral immunity by inhibiting a novel regulator, RESIST, which decreases the stability of Ifnb1 mRNA and thereby suppresses interferon expression. Notably, RESIST is the orthologue of human ANXA2R. This finding highlights the crucial role of ANXA2R in cellular signaling and immune responses.