APPBP2 Polyclonal antibody, PBS Only

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• APPBP2 Polyclonal antibody, PBS Only (12409-1-PBS)

• 

  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

APPBP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 12409-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

12409-1-PBS targets APPBP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag3092

  Product name: Recombinant human APPBP2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 288-586 aa of BC018121

  Sequence: SDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

• Full Name: amyloid beta precursor protein (cytoplasmic tail) binding protein 2
• Calculated Molecular Weight: 585 aa, 67 kDa
• Observed Molecular Weight: 67 kDa
• GenBank Accession Number: BC018121
• Gene Symbol: APPBP2
• Gene ID (NCBI): 10513
• RRID: AB_2918029
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q92624
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Amyloid proteinbinding protein 2 (APPBP2) is a hydrophilic tubulin that interacts with microtubules and is functionally involved in beta-amyloid precursor protein (APP) transport and/or processing. Based on the regulation of microtubules and APP, APPBP2 is found to be involved in the oncogenesis of various types of cancers, such as breast cancer, ovarian clear cell adenocarcinomas, desmoplastic medulloblastomas and neuroblastomas. Recently, Studies have demonstrated that APPBP2 is a potential target for diagnosis and therapeutic intervention in non-small cell lung cancer (NSCLC) (PMID: 31105033).