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ARHGAP10 Polyclonal antibody, PBS Only (55139-1-PBS)

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WB analysis of mouse heart using 55139-1-AP (same clone as 55139-1-PBS)
mouse heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
WB analysis of human heart using 55139-1-AP (same clone as 55139-1-PBS)
human heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
WB analysis of mouse kidney using 55139-1-AP (same clone as 55139-1-PBS)
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
WB analysis of HEK-293 using 55139-1-AP (same clone as 55139-1-PBS)
HEK-293 cells were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.
IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

Featured Product
KD/KO Validated

ARHGAP10 Polyclonal antibody, PBS Only

Name: ARHGAP10 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 55139-1-PBS

ARHGAP10 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 55139-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

Request bulk or custom quote

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

55139-1-PBS targets ARHGAP10 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity	human, mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide Predict reactive species
Full Name	Rho GTPase activating protein 10
Calculated Molecular Weight	89 kDa
Observed Molecular Weight	89 kDa
GenBank Accession Number	NM_024605
Gene Symbol	ARHGAP10
Gene ID (NCBI)	79658
RRID	AB_10794449
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	A1A4S6
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

ARHGAP10, also named as GRAF2, is GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. It is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. ARHGAP10 inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. It stabilizes PAK-2p34 thereby increasing stimulation of cell death. The antibody is specific to ARHGAP10.