ARMC2 Polyclonal antibody, PBS Only

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• ARMC2 Polyclonal antibody, PBS Only (24011-1-PBS)

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  WB analysis using 24011-1-AP (same clone as 24011-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24011-1-AP (ARMC2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24011-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse testis using 24011-1-AP (same clone as 24011-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse testis tissue using ARMC2 antibody (24011-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24011-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 24011-1-AP (same clone as 24011-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse brain tissue using ARMC2 antibody (24011-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 24011-1-PBS in a different storage buffer formulation.

ARMC2 Polyclonal Antibody for WB, IF-Fro, Indirect ELISA

Cat No. 24011-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF-Fro, Indirect ELISA

Synonyms

armadillo repeat containing 2, ARMC 2, RP11 787I22.1

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Product Information

24011-1-PBS targets ARMC2 in WB, IF-Fro, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag21162

  Product name: Recombinant human ARMC2 protein

  Source: e coli.-derived, PET30a

  Tag: 6*His

  Domain: 510-860 aa of BC030603

  Sequence: CYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIQTLLSLFQTFHQLDLHSQKPVGQRGEQHRAQRPPSEAEDVLIKLTRVLANIAIHPGVGPVLAANPGIVGLLLTTLEYKSLDDCEELVINATATINNLSYYQVKNSIIQDKKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDVCDFIVQNNVHRFMMALLDAQHQDICFSACGVLLNLTVDKDKRVILKEGGGIKKLVDCLRDLGPTDWQLACLVCKTLWNFSENITNASSCFGNEDTNTLLLLLSSFLDEELALDGSFDPDLKNYHKLHWETEFKPVAQQLLNRIQRHHTFLEPLPIPSF

• Full Name: armadillo repeat containing 2
• Calculated Molecular Weight: 867 aa, 97 kDa
• Observed Molecular Weight: 78 kDa,97 kDa
• GenBank Accession Number: BC030603
• Gene Symbol: ARMC2
• Gene ID (NCBI): 84071
• RRID: AB_3669428
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: Q8NEN0
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The ARMC2 protein (Armadillo Repeat Containing 2) is an evolutionarily conserved axonemal-related protein that plays a crucial role in the structure and function of cilia and flagella. It interacts with the kinesin-2 complex through its unique Armadillo repeat domain and acts as an adapter for the flagellar transport (IFT) process, responsible for transporting specific cargoes (such as the precursor proteins necessary for the construction of flagellar axons) from the cell body to the flagellar tip, which is essential for the assembly, maintenance, and signal transduction functions of the flagella. Its dysfunction is directly related to abnormal sperm flagellar morphology and movement disorders.