Product Information
17351-1-PBS targets ASTN2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11425 Product name: Recombinant human ASTN2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-440 aa of BC029272 Sequence: MNTLLCKGMFCLLSWEADSRGRLGEYTLQPLSLQTEETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKIMCEEKMVSMARNTYGESKGR Predict reactive species |
| Full Name | astrotactin 2 |
| Calculated Molecular Weight | 440 aa, 50 kDa |
| Observed Molecular Weight | 148 kDa |
| GenBank Accession Number | BC029272 |
| Gene Symbol | ASTN2 |
| Gene ID (NCBI) | 23245 |
| RRID | AB_2878394 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75129 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
ASTN2, also named as KIAA0634, has recently been implicated in several common disorders of the nervous system, including attention deficit hyperactivity disorder (ADHD), autism and schizophrenia. Astn2 is abundant in migrating cerebellar granule neurons when glial-guided migration is ongoing. ASTN2 forms a complex with ASTN1 that regulates the polarized trafficking of ASTN1 during migration.
