ATN1 Polyclonal antibody, PBS Only

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  WB analysis of mouse testis using 19243-1-AP (same clone as 19243-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 19243-1-AP (ATN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19243-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 19243-1-AP (same clone as 19243-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tissue slide using 19243-1-AP (ATN1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 19243-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 19243-1-AP (same clone as 19243-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tissue slide using 19243-1-AP (ATN1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 19243-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 19243-1-AP (same clone as 19243-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 19243-1-AP (ATN1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 19243-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 19243-1-AP (same clone as 19243-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 19243-1-AP (ATN1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 19243-1-PBS in a different storage buffer formulation.

ATN1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 19243-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

atrophin 1, Atrophin1, Atrophin-1, B37, Dentatorubral-pallidoluysian atrophy protein

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Product Information

19243-1-PBS targets ATN1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag5835

  Product name: Recombinant human ATN1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 842-1191 aa of BC051795

  Sequence: LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL

• Full Name: atrophin 1
• Calculated Molecular Weight: 125 kDa
• Observed Molecular Weight: 105-110 kDa
• GenBank Accession Number: BC051795
• Gene Symbol: ATN1
• Gene ID (NCBI): 1822
• RRID: AB_2878575
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P54259
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ATN1 also known as Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat.