ATN1 Polyclonal antibody

ATN1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 19243-1-AP

Synonyms

ATN1, atrophin 1, B37, D12S755E, DRPLA, HRS, NOD



Tested Applications

Positive WB detected inmouse testis tissue
Positive IHC detected inhuman ovary tissue, human testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 19243-1-AP is ATN1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ATN1 fusion protein Ag5835
Full Name atrophin 1
Calculated molecular weight 125 kDa
Observed molecular weight 105-110 kDa
GenBank accession numberBC051795
Gene symbol ATN1
Gene ID (NCBI) 1822
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ATN1 also known as Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat.

Protocols

Product Specific Protocols
WB protocol for ATN1 antibody 19243-1-APDownload protocol
IHC protocol for ATN1 antibody 19243-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols