Arp5/ACTR5 Monoclonal antibody

Arp5/ACTR5 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1E11C1

Cat no : 67326-1-Ig

Synonyms

Actin related protein 5, ACTR5, Arp5, FLJ12785, hARP5, INO80M, Sarcoma antigen NY SAR 16



Tested Applications

Positive WB detected inHepG2 cells, C2C12 cells, rat skeletal muscle tissue, pig skeletal muscle tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Product Information

67326-1-Ig targets Arp5/ACTR5 in WB,ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Reactivity Human, mouse, rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Arp5/ACTR5 fusion protein Ag15976
Full Name ARP5 actin-related protein 5 homolog (yeast)
Calculated molecular weight 607 aa, 68 kDa
Observed molecular weight 68 kDa
GenBank accession numberBC038402
Gene symbol ACTR5
Gene ID (NCBI) 79913
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

Arp5 is a member of nuclear actin-related proteins (ARPs) that function as components of the chromatin- remodeling complex. Recently study reported that Arp5 regulates smooth muscle cell differentiation through interaction with myocardin (Myocd). Arp5 has been identified as negative regulator of Myocd, suppressing Myocd activity in the nucleus through tightly binding with Myocd RPEL motifs. Alternative splicing results in two variants of Arp5: a broadly expressed arp5-common, and a smooth muscle restricted arp5-sm. Expression of Arp5-sm protein is strongly suppressed in well-differentiated smooth muscle cells by partial messenger RNA decay and translational suppression. (24567363)

Protocols

Product Specific Protocols
WB protocol for Arp5/ACTR5 antibody 67326-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols