Product Information
33437-1-PBS targets BAZ2B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36147 Product name: Recombinant human BAZ2B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1833-2080 aa of NM_013450.3 Sequence: DNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKL Predict reactive species |
| Full Name | bromodomain adjacent to zinc finger domain, 2B |
| Calculated Molecular Weight | 240kDa,2168aa |
| Observed Molecular Weight | 220-240 kDa |
| GenBank Accession Number | NM_013450.3 |
| Gene Symbol | BAZ2B |
| Gene ID (NCBI) | 29994 |
| RRID | AB_3742971 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9UIF8 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
BAZ2B(Bromodomain adjacent to zinc finger domain protein 2) is a regulatory subunit of the ATP-dependent chromatin remodeling complexes BRF1 and BRF5, which control access to DNA during DNA-templated processes. BAZ2B has been implicated in several diseases and also in unhealthy ageing. Loss of BAZ2B function has been postulated to cause neurodevelopmental disorders (PMID: 31999386, 31999386).

